Understanding TRALI and TACO in Blood Transfusion

Slide 1: Understanding Blood Transfusion Reactions

• Blood transfusion reactions are adverse events occurring during or after transfusion, often due to immune responses or other complications.
• Two significant reactions include Transfusion-Related Acute Lung Injury (TRALI) and Transfusion-Associated Circulatory Overload (TACO), both impacting patient safety.
• TRALI is characterized by acute respiratory distress following transfusion, linked to donor antibodies targeting recipient leukocytes.
• TACO refers to volume overload from transfusion, leading to pulmonary edema, particularly in high-risk patients like the elderly or heart failure cases.
• Understanding these reactions is crucial for clinicians to implement preventive strategies and ensure patient safety during transfusions.

Slide 2: Understanding TRALI Effects

Slide 3: Understanding Transfusion Associated Circulatory Overload (TACO)

Slide 4: TRALI vs TACO: Common Clinical Signs

Slide 5: Understanding Transfusion Reactions

Slide 6: Key Symptoms of TACO

Slide 7: Understanding TRALI Symptoms

Slide 8: Nursing Role in TACO Management

Slide 9: Nursing Role in TRALI Management

Slide 10: Comparing TACO and TRALI

Slide 11: Preventing Transfusion Reactions

Slide 12: TACO & TRALI: Key Takeaways